The Kallikrein 1 Polyclonal Antibody (CAB1807) offered by Assay Genie is a valuable tool for research involving Kallikrein 1, a serine protease involved in various physiological processes such as blood pressure regulation and skin desquamation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.Kallikrein 1, also known as tissue kallikrein, is known to be involved in the modulation of inflammatory responses and is overexpressed in certain cancers, making it a target of interest in cancer research. The Kallikrein 1 Polyclonal Antibody enables detection and analysis of Kallikrein 1 protein levels in different cell types, allowing researchers to further explore its role in disease pathology and potential therapeutic applications.
By understanding the function and regulation of Kallikrein 1, researchers can uncover its potential implications in cancer progression, inflammatory diseases, and other pathological conditions. The Kallikrein 1 Polyclonal Antibody provides a reliable tool for investigating the role of Kallikrein 1 in various biological processes and disease settings.
Product Name:
KLK1 Rabbit Polyclonal Antibody
SKU:
CAB1807
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-262 of human KLK1 (NP_002248.1).
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.
Purification Method:
Affinity purification
Gene ID:
3816
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using KLK1 Rabbit pAb (CAB1807) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
