The KLHL8 Polyclonal Antibody (CAB14917) provided by Assay Genie is specifically designed for research involving KLHL8, a protein that plays a critical role in cellular functions. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in various applications, including Western blot and immunofluorescence.KLHL8 is a Kelch-like ECH-associated protein 1 (Keap1) interacting protein that regulates the Keap1-Nrf2 pathway, which is involved in the cellular response to oxidative stress. The antibody binds specifically to the KLHL8 protein, allowing for accurate detection and analysis in different cell types.
This makes it an ideal tool for studying the role of KLHL8 in cellular processes, particularly in the context of oxidative stress-related diseases and conditions.With its potential implications in various diseases, including cancer and neurodegenerative disorders, understanding the function of KLHL8 is crucial for developing targeted therapies and treatments. The KLHL8 Polyclonal Antibody from Assay Genie provides researchers with a reliable tool to further investigate the role of KLHL8 in disease pathology and potential therapeutic interventions.
Product Name:
KLHL8 Rabbit Polyclonal Antibody
SKU:
CAB14917
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 271-620 of human KLHL8 (NP_065854.3).
Involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Located in nucleoplasm. Part of Cul3-RING ubiquitin ligase complex.
Purification Method:
Affinity purification
Gene ID:
57563
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KLHL8 Rabbit pAb (CAB14917) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
