The KLHL32 Polyclonal Antibody (PACO10139) is a valuable tool for researchers studying KLHL32, a key player in the regulation of protein degradation and cell growth. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot analysis. By binding specifically to the KLHL32 protein, this antibody enables the accurate detection and examination of KLHL32 expression in various cell types, making it an ideal choice for investigations in cellular biology and cancer research.KLHL32 is a substrate adaptor protein that mediates the degradation of target proteins through the ubiquitin-proteasome system, thereby influencing essential cellular processes such as cell cycle progression and signal transduction.
Dysregulation of KLHL32 has been linked to various disease states, including cancer and neurodegenerative disorders, highlighting its significance as a potential therapeutic target. By studying the role of KLHL32 in cellular functions, researchers can gain valuable insights into disease mechanisms and identify potential strategies for targeted intervention.
KLHL32: 3 isoforms of the human protein are produced by alternative splicingChromosomal Location of Human Ortholog: 6q16.1Molecular Function: ubiquitin-protein ligase activityBiological Process: protein ubiquitination during ubiquitin-dependent protein catabolic process
