The KLHL29 Antibody (PAC02282) is a valuable tool for researchers studying the KLHL29 protein, a substrate recognition component of the Cullin3-based E3 ubiquitin ligase complex. This polyclonal antibody, specifically raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to KLHL29, the antibody enables precise detection and analysis in various cell types, making it an ideal choice for investigations in molecular biology and protein degradation pathways.KLHL29 participates in the ubiquitination process, which plays a crucial role in regulating protein turnover and cellular homeostasis.
As a key player in the Cullin3-based E3 ligase complex, KLHL29 is involved in targeting specific proteins for degradation, impacting various cellular processes such as cell cycle progression, signal transduction, and response to cellular stress. Research on KLHL29 is essential for understanding its function and potential implications in diseases related to protein dysregulation, making this antibody a valuable asset for studies in areas such as cancer biology and neurodegenerative disorders.
Antibody Name:
KLHL29 Antibody (PACO22382)
Antibody SKU:
PACO22382
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:50-1:100
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from internal of human KLHL29.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Immunohistochemistry analysis of paraffin-embedded human brain tissue using KLHL29 antibody.
Synonyms:
Kelch-like protein 29; Kelch repeat and BTB domain-containing protein 9;
UniProt Protein Function:
KLHL29: 2 isoforms of the human protein are produced by alternative splicingChromosomal Location of Human Ortholog: 2p24.1
