The KLHL18 Polyclonal Antibody (PAC010132) is a valuable tool for researchers studying KLHL18, a substrate-specific adapter of the Cullin 3-based E3 ubiquitin ligase complex. This antibody, generated in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. With its ability to bind to the KLHL18 protein, researchers can easily detect and analyze KLHL18 expression in various cell types, making it an ideal choice for studies in cell biology and protein degradation pathways.
KLHL18 is known for its role in targeting specific substrates for ubiquitination and subsequent degradation by the proteasome, playing a crucial role in cell cycle regulation and maintenance of cellular homeostasis. Understanding the function of KLHL18 is essential for unraveling the mechanisms underlying protein turnover and degradation, making this antibody a valuable asset for research into cellular processes and potential therapeutic targets.
