The KLHL1 Polyclonal Antibody (CAB14594) is a valuable tool for researchers studying KLHL1, a protein involved in cellular functions and signaling pathways. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blotting applications. By binding specifically to the KLHL1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in biochemistry and cell biology.KLHL1 is known for its role in mediating protein-protein interactions and regulating intracellular processes, such as protein degradation and cytoskeleton organization.
Dysfunction of KLHL1 has been implicated in diseases like neurodegenerative disorders, cancer, and muscle diseases, highlighting its importance as a potential therapeutic target. By deciphering the mechanisms of action of KLHL1, researchers can gain insights into disease processes and develop new strategies for treatment and intervention.
Product Name:
KLHL1 Rabbit Polyclonal Antibody
SKU:
CAB14594
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human KLHL1 (NP_065917.1).
The KLHL1 protein belongs to a family of actin-organizing proteins related to Drosophila Kelch (Nemes et al., 2000 [PubMed 10888605]).
Purification Method:
Affinity purification
Gene ID:
57626
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from A-431 cells, using KLHL1 Rabbit pAb (CAB14594) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
