KLHDC8A Antibody (PACO37846)
- SKU:
- PACO37846
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | KLHDC8A Antibody (PACO37846) |
| Antibody SKU: | PACO37846 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Kelch domain-containing protein 8A protein (1-350AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: KLHDC8A antibody at 0.5µg/ml. Lane 1: Jurkat whole cell lysate. Lane 2: Mouse liver tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 39 kDa. Observed band size: 39 kDa. |
 | Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO37846 at dilution of 1:100. |
| Background: | Cul3-RING ubiquitin ligase complex, protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
| Synonyms: | Kelch domain-containing protein 8A (Substitute for delta-EGFR expression 1) (S-delta-E1), KLHDC8A |
| UniProt Protein Function: | KLHDC8A: Protein type: Unknown functionChromosomal Location of Human Ortholog: 1q32.1Molecular Function: ubiquitin-protein ligase activityBiological Process: protein ubiquitination during ubiquitin-dependent protein catabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a kelch domain-containing protein which is upregulated in cancer. Upregulated expression of the encoded protein may provide an alternative pathway for tumors to maintain aggressiveness in the absence of epidermal growth factor receptor dependence. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012] |
| UniProt Code: | Q8IYD2 |
| NCBI GenInfo Identifier: | 428229668 |
| NCBI Gene ID: | 55220 |
| NCBI Accession: | NP_001258792.1 |
| UniProt Secondary Accession: | Q8IYD2,Q9NVG5, B3KU70 |
| UniProt Related Accession: | Q8IYD2 |
| Molecular Weight: | 38,859 Da |
| NCBI Full Name: | kelch domain-containing protein 8A |
| NCBI Synonym Full Names: | kelch domain containing 8A |
| NCBI Official Symbol: | KLHDC8AÂ Â |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | kelch domain-containing protein 8A |
| UniProt Protein Name: | Kelch domain-containing protein 8A |
| UniProt Synonym Protein Names: | Substitute for delta-EGFR expression 1; S-delta-E1 |
| Protein Family: | Kelch domain-containing protein |
| UniProt Gene Name: | KLHDC8AÂ Â |
| UniProt Entry Name: | KLD8A_HUMAN |