The KLHDC3 Polyclonal Antibody (CAB13741) is a crucial tool for researchers studying KLHDC3, a protein involved in various cellular processes such as protein degradation and cell cycle regulation. This antibody is produced in rabbits and has been validated for use in Western blot applications, providing reliable and accurate detection of the KLHDC3 protein in human samples.KLHDC3, a Kelch domain-containing protein, is known to interact with other proteins involved in ubiquitin-mediated protein degradation, suggesting a role in maintaining protein homeostasis within cells. Its function in the cell cycle and potential implications in disease make it an intriguing target for further investigation in research areas such as cancer biology, cell signaling, and molecular biology.
By utilizing the KLHDC3 Polyclonal Antibody, researchers can gain valuable insights into the expression levels and localization of KLHDC3 in different cell types and tissues, aiding in the understanding of its biological functions and potential therapeutic implications. This antibody is a valuable tool for studies aimed at unraveling the intricate mechanisms underlying KLHDC3-mediated cellular processes.
Product Name:
KLHDC3 Rabbit Polyclonal Antibody
SKU:
CAB13741
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-382 of human KLHDC3 (NP_476502.1).
The protein encoded by this gene contains six repeated kelch motifs that are structurally similar to recombination activating gene 2, a protein involved in the activation of the V(D)J recombination. In mouse, this gene is found to be expressed specifically in testis. Its expression in pachytene spermatocytes is localized to cytoplasma and meiotic chromatin, suggesting that this gene may be involved in meiotic recombination.
Purification Method:
Affinity purification
Gene ID:
116138
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KLHDC3 Rabbit pAb (CAB13741) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
