Anti-KLHDC2 Antibody (CAB15146)
- SKU:
- CAB15146
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Anti-KLHDC2 Antibody (CAB15146)
The KLHDC2 Polyclonal Antibody (CAB15146) is a valuable tool for researchers studying the KLHDC2 protein, which plays a role in regulating various cellular processes. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the KLHDC2 protein, this antibody allows for the detection and analysis of KLHDC2 in a variety of cell types, making it an ideal choice for studies in cell biology and molecular biology.KLHDC2 is a protein involved in protein degradation pathways and has been linked to the regulation of cell cycle progression and cell growth.
Understanding the function of KLHDC2 is important for identifying its role in disease processes such as cancer, neurodegenerative disorders, and metabolic conditions. By using the KLHDC2 Polyclonal Antibody, researchers can gain insights into the mechanisms by which KLHDC2 influences cellular functions, leading to potential therapeutic targets for various diseases.
| Antibody Name: | Anti-KLHDC2 Antibody |
| Antibody SKU: | CAB15146 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human KLHDC2 (NP_055130.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human KLHDC2 (NP_055130.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MADG NEDL RADD LPGP AFES YESM ELAC PAER SGHV AVSD GRHM FVWG GYKS NQVR GLYD FYLP REEL WIYN METG RWKK INTE GDVP PSMS GSCA VCVD RVLY LFGG HHSR GNTN KFYM LDSR STDR VLQW ERID CQGI PPSS KDKL GVWV YKNK LIFF GGYG YLPE DKVL GTFE FDET SFWN SSHP RGWN DHVH ILDT ETFT WSQP ITTG KAPS PRAA HACA TVGN RGFV FGGR YRDA |
| Gene ID: | 23588 |
| Uniprot: | Q9Y2U9 |
| Cellular Location: | Nucleus |
| Calculated MW: | 28kDa/46kDa |
| Observed MW: | Refer to figures |
| Synonyms: | KLHDC2, HCLP-1, HCLP1, LCP |
| Background: |
| UniProt Protein Function: | KLHDC2: Represses CREB3-mediated transcription by interfering with CREB3-DNA binding. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 14q21.3 Cellular Component: nuclear membrane; nucleus |
| UniProt Code: | Q9Y2U9 |
| NCBI GenInfo Identifier: | 28380093 |
| NCBI Gene ID: | 23588 |
| NCBI Accession: | Q9Y2U9.1 |
| UniProt Secondary Accession: | Q9Y2U9,Q6IAF0, Q86TY9, B3KPF9, |
| UniProt Related Accession: | Q9Y2U9 |
| Molecular Weight: | 28,198 Da |
| NCBI Full Name: | Kelch domain-containing protein 2 |
| NCBI Synonym Full Names: | kelch domain containing 2 |
| NCBI Official Symbol: | KLHDC2Â Â |
| NCBI Official Synonym Symbols: | LCP; HCLP1; HCLP-1Â Â |
| NCBI Protein Information: | kelch domain-containing protein 2 |
| UniProt Protein Name: | Kelch domain-containing protein 2 |
| UniProt Synonym Protein Names: | Hepatocellular carcinoma-associated antigen 33; Host cell factor homolog LCP; Host cell factor-like protein 1; HCLP-1 |
| Protein Family: | Kelch domain-containing protein |
| UniProt Gene Name: | KLHDC2Â Â |
| UniProt Entry Name: | KLDC2_HUMAN |
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