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KLF7 Transcription Factor Activity Assay

SKU:
TFAB00194
Product Type:
ELISA Kit
ELISA Type:
Transcription Factor Assay
Analytes:
KLF7
Reactivity:
Human
Mouse
$719
Frequently bought together:

Description

system_update_altDatasheet

KLF7 Transcription Factor Activity Assay

The KLF7 Transcription Factor Activity Assay Kit is a cutting-edge tool for measuring the transcriptional activity of KLF7 in cell lysates. KLF7 is a key transcription factor that regulates gene expression and plays a critical role in various biological processes, including cell differentiation, proliferation, and development.This assay kit offers high sensitivity and specificity, allowing for accurate quantification of KLF7 activity in a variety of cell types and experimental conditions. Its user-friendly format and quick assay time make it ideal for high-throughput screening and detailed mechanistic studies.

By using the KLF7 Transcription Factor Activity Assay Kit, researchers can gain valuable insights into the regulatory mechanisms controlled by KLF7 and its impact on cellular functions. This kit is essential for investigating KLF7's role in disease progression, such as cancer, diabetes, and neurological disorders, and for developing novel therapeutic strategies targeting KLF7 activity.

Product Name:KLF7 Transcription Factor Activity Assay
Product Code:TFAB00194
Target:KLF7
Reactivity:Human, Mouse
Sample Types:Nuclear or cell lysates

The Assay Genie KLF7 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates

Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.

Assay Time:4.5 hours
Detection Method:Colorimetric 450 nm
Size:12 x 8-Well Microstrips
Storage:4°C for 6 months
UniProt Protein Function:KLF7: Transcriptional activator. Binds in vitro to the CACCC motif of the beta-globin promoter and to the SP1 recognition sequence. Belongs to the krueppel C2H2-type zinc-finger protein family.
UniProt Protein Details:

Protein type:DNA-binding; C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 2q32

Cellular Component: nucleus

Molecular Function:DNA binding; zinc ion binding; transcription coactivator activity; transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; axon guidance; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; dendrite morphogenesis

NCBI Summary:The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
UniProt Code:O75840
NCBI GenInfo Identifier:401709918
NCBI Gene ID:8609
NCBI Accession:NP_001257871.1
UniProt Secondary Accession:O75840,Q7Z3H8, Q96E51, B2RB03, B7Z4F7, C9JF04, E7EWH1 L0R4P2,
UniProt Related Accession:O75840
Molecular Weight:33kd
NCBI Full Name:Krueppel-like factor 7 isoform 2
NCBI Synonym Full Names:Kruppel-like factor 7 (ubiquitous)
NCBI Official Symbol:KLF7  
NCBI Official Synonym Symbols:UKLF  
NCBI Protein Information:Krueppel-like factor 7
UniProt Protein Name:Krueppel-like factor 7
UniProt Synonym Protein Names:Ubiquitous krueppel-like factor
Protein Family:Krueppel-like factor
UniProt Gene Name:KLF7  
UniProt Entry Name:KLF7_HUMAN
Antibodies
Anti-KLF7 Antibody (CAB8879)
KLF7 Antibody (PACO05586)
KLF7 Antibody (PACO10127)
KLF7 Antibody (PACO14617)
KLF7 Antibody (PACO14618)

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