KLF7 Transcription Factor Activity Assay
- SKU:
- TFAB00194
- Product Type:
- ELISA Kit
- ELISA Type:
- Transcription Factor Assay
- Analytes:
- KLF7
- Reactivity:
- Human
- Mouse
Description
| Product Name: | KLF7 Transcription Factor Activity Assay |
| Product Code: | TFAB00194 |
| Target: | KLF7 |
| Reactivity: | Human, Mouse |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie KLF7 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | KLF7: Transcriptional activator. Binds in vitro to the CACCC motif of the beta-globin promoter and to the SP1 recognition sequence. Belongs to the krueppel C2H2-type zinc-finger protein family. |
| UniProt Protein Details: | Protein type:DNA-binding; C2H2-type zinc finger protein Chromosomal Location of Human Ortholog: 2q32 Cellular Component: nucleus Molecular Function:DNA binding; zinc ion binding; transcription coactivator activity; transcription factor activity Biological Process: regulation of transcription from RNA polymerase II promoter; axon guidance; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; dendrite morphogenesis |
| NCBI Summary: | The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] |
| UniProt Code: | O75840 |
| NCBI GenInfo Identifier: | 401709918 |
| NCBI Gene ID: | 8609 |
| NCBI Accession: | NP_001257871.1 |
| UniProt Secondary Accession: | O75840,Q7Z3H8, Q96E51, B2RB03, B7Z4F7, C9JF04, E7EWH1 L0R4P2, |
| UniProt Related Accession: | O75840 |
| Molecular Weight: | 33kd |
| NCBI Full Name: | Krueppel-like factor 7 isoform 2 |
| NCBI Synonym Full Names: | Kruppel-like factor 7 (ubiquitous) |
| NCBI Official Symbol: | KLF7Â Â |
| NCBI Official Synonym Symbols: | UKLFÂ Â |
| NCBI Protein Information: | Krueppel-like factor 7 |
| UniProt Protein Name: | Krueppel-like factor 7 |
| UniProt Synonym Protein Names: | Ubiquitous krueppel-like factor |
| Protein Family: | Krueppel-like factor |
| UniProt Gene Name: | KLF7Â Â |
| UniProt Entry Name: | KLF7_HUMAN |
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