The KLF6 Polyclonal Antibody (CAB10011) is a valuable tool for researchers studying KLF6, a transcription factor involved in various cellular processes, including cell growth, differentiation, and apoptosis. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blotting applications. By targeting the KLF6 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it ideal for research in fields such as cancer biology and developmental biology.
KLF6, also known as Krüppel-like factor 6, is a key player in the regulation of gene expression and has been implicated in the development and progression of various diseases, including cancer and cardiovascular disorders. Its multifaceted roles in cell proliferation, differentiation, and apoptosis make it a promising target for therapeutic interventions aimed at modulating these processes. By studying the functions of KLF6, researchers can gain valuable insights into disease mechanisms and identify potential targets for drug development.
Product Name:
KLF6 Rabbit Polyclonal Antibody
SKU:
CAB10011
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 40-200 of human KLF6 (NP_001291.3).
This gene encodes a member of the Kruppel-like family of transcription factors. The zinc finger protein is a transcriptional activator, and functions as a tumor suppressor. Multiple transcript variants encoding different isoforms have been found for this gene, some of which are implicated in carcinogenesis.
Purification Method:
Affinity purification
Gene ID:
1316
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from PC-3 cells, using KLF6 Rabbit pAb (CAB10011) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
