The KLF5 Polyclonal Antibody (CAB2989) is a powerful tool for researchers studying the function of KLF5, a key transcription factor involved in various cellular processes, including cell growth, differentiation, and development. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples and has been validated for use in Western blot applications.KLF5, also known as Krüppel-like factor 5, is known to play a crucial role in regulating gene expression and cell proliferation, making it a pivotal player in cancer research and developmental biology.
By targeting KLF5 with this polyclonal antibody, researchers can detect and analyze the protein in different cell types, providing valuable insights into its function and potential implications in disease pathology.The versatility of the KLF5 Polyclonal Antibody makes it an ideal tool for studying the molecular mechanisms underlying various physiological and pathological conditions, such as cancer, cardiovascular diseases, and diabetes. By elucidating the role of KLF5 in these contexts, researchers can potentially uncover new therapeutic targets for the treatment of these diseases.
Product Name:
KLF5 Rabbit Polyclonal Antibody
SKU:
CAB2989
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human KLF5 (NP_001721.2).
This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
688
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using KLF5 Rabbit pAb (CAB2989) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
