KLF4 Polyclonal Antibody (CAB21709)
- SKU:
- CAB21709
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
| Product Name: | KLF4 Polyclonal Antibody |
| SKU: | CAB21709 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-479 of human KLF4 (NP_004226.3). |
| Sequence: | PPTA PFNL ADIN DVSP SGGF VAEL LRPE LDPV YIPP QQPQ PPGG GLMG KFVL KASL SAPG SEYG SPSV ISVS KGSP DGSH PVVV APYN GGPP RTCP KIKQ EAVS SCTH LGAG PPLS NGHR PAAH DFPL GRQL PSRT TPTL GLEE VLSS RDCH PALP LPPG FHPH PGPN YPSF LPDQ MQPQ VPPL HYQE LMPP GSCM PEEP KPKR GRRS WPRK RTAT HTCD YAGC GKTY TKSS HLKA HLRT HTGE KPYH CDWD GCGW KFAR SDEL TRHY RKHT GHRP FQCQ KCDR AFSR SDHL ALHM KRHF |
| Tested Applications: | WB ELISA |
| Recommended Dilution: | WB,1:500 - 1:1000 |
| Synonyms: | EZF; GKLF; KLF4 |
| Positive Sample: | Hela,HCT 116,HT-29 |
| Conjugate: | Unconjugated |
| Cellular Localization: | Nucleus. |
| Calculated MW: | 55kDa |
| Observed MW: | Refer to figures |
This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms.
| Purification Method: | Affinity purification |
| Gene ID: | 9314 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
 | Western blot analysis of various lysates using KLF4 Rabbit pAb (CAB21709) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s. |
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