KLF4 Rabbit Polyclonal Antibody (CAB6640)
- SKU:
- CAB6640
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | KLF4 Rabbit Polyclonal Antibody |
SKU: | CAB6640 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of KLF4 (NP_001300981.1). |
Sequence: | MRQP PGES DMAV SDAL LPSF STFA SGPA GREK TLRQ AGAP NNRW REEL SHMK RLPP VLPG RPYD LAAA TVAT DLES GGAG AACG GSNL APLP RRET EEFN DLLD LDFI LSNS LTH |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | EZF; GKLF; KLF4 |
Positive Sample: | HeLa,HCT116,HT-29 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 55kDa |
Observed MW: | 62kDa |
This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 9314 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |