The KLF3 Polyclonal Antibody (CAB7195) is a valuable tool for researchers studying the Kruppel-like factor 3 (KLF3) protein, a transcription factor involved in various cellular processes such as differentiation, proliferation, and apoptosis. This antibody, produced in rabbits, demonstrates high specificity and sensitivity towards human samples, making it suitable for use in Western blot applications.KLF3 is known to play a pivotal role in the regulation of gene expression, particularly in the context of development, metabolism, and immune response. Dysregulation of KLF3 has been linked to various diseases, including cancer, cardiovascular disorders, and metabolic syndromes, highlighting its potential as a therapeutic target.
By utilizing the KLF3 Polyclonal Antibody, researchers can effectively detect and analyze the expression of KLF3 in different cell types, providing insights into its function and potential implications in disease pathology. This antibody is a valuable tool for studies in molecular biology, genetics, and therapeutic development, offering a deeper understanding of KLF3-mediated cellular processes and disease mechanisms.
Product Name:
KLF3 Rabbit Polyclonal Antibody
SKU:
CAB7195
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human KLF3 (NP_057615.3).
Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
51274
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using KLF3 antibody (CAB7195) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 60s.