The KLF2 Polyclonal Antibody (CAB16480) is a valuable tool for research involving KLF2, a transcription factor that plays a key role in immune regulation and vascular development. This antibody, raised in rabbits, is highly specific and reacts with human samples, making it ideal for use in various research applications such as Western blot and immunohistochemistry.KLF2, also known as Krüppel-like factor 2, is involved in the regulation of genes that control inflammation, cell cycle, and vascular smooth muscle cell function.
Its importance in maintaining immune homeostasis and cardiovascular health makes it a promising target for studying diseases like atherosclerosis, hypertension, and inflammatory disorders. The KLF2 Polyclonal Antibody enables detection and analysis of KLF2 protein levels in different cell types, providing valuable insights for researchers in immunology and cardiovascular research fields.
Product Name:
KLF2 Rabbit Polyclonal Antibody
SKU:
CAB16480
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human KLF2 (NP_057354.1).
This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is expressed early in mammalian development and is found in many different cell types. The protein acts to bind the CACCC box found in the promoter of target genes to activate their transcription. It plays a role in many processes during development and disease including adipogenesis, embryonic erythropoiesis, epithelial integrity, inflammation and t-cell viability.
Purification Method:
Affinity purification
Gene ID:
10365
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using KLF2 Rabbit pAb (CAB16480) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
