The KLF14 Polyclonal Antibody (CAB18607) is a valuable tool for researchers studying KLF14, a transcription factor involved in the regulation of gene expression and cellular processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By binding specifically to the KLF14 protein, this antibody enables the detection and analysis of KLF14 in various cell types, making it an ideal choice for studies in molecular biology and cancer research.KLF14 is a key player in the control of gene expression, influencing a wide range of biological functions such as cell proliferation, differentiation, and metabolism.
Dysregulation of KLF14 has been implicated in various diseases, including cancer, diabetes, and cardiovascular disorders, highlighting its potential as a therapeutic target. By investigating the role of KLF14 in these conditions, researchers can gain insights into disease mechanisms and potentially identify new treatment strategies.Overall, the KLF14 Polyclonal Antibody (CAB18607) offers researchers a reliable tool for studying the function of KLF14 in health and disease, paving the way for advancements in precision medicine and personalized treatments.
Product Name:
KLF14 Rabbit Polyclonal Antibody
SKU:
CAB18607
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human KLF14 (NP_619638.2).
This intronless gene encodes a member of the Kruppel-like family of transcription factors. The encoded protein functions as a transcriptional co-repressor, and is induced by transforming growth factor-beta (TGF-beta) to repress TGF-beta receptor II gene expression. This gene exhibits imprinted expression from the maternal allele in embryonic and extra-embryonic tissues.
Purification Method:
Affinity purification
Gene ID:
136259
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KLF14 Rabbit pAb (CAB18607) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
