The KLF11 Polyclonal Antibody (CAB18659) is a valuable tool for researchers studying KLF11, a transcription factor known for its roles in various biological processes such as cell growth, differentiation, and metabolism. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.KLF11, also known as Krüppel-like factor 11, is involved in the regulation of gene expression and has been linked to diseases such as diabetes and cancer. By targeting the KLF11 protein, researchers can investigate its function in different cell types and gain insights into its impact on physiological and pathological processes.
This antibody is suitable for immunology and cancer research, providing a reliable tool for the detection and analysis of KLF11 in diverse experimental settings.Understanding the role of KLF11 is essential for elucidating its molecular mechanisms and potential therapeutic applications in diseases associated with dysregulated gene expression. The KLF11 Polyclonal Antibody offers researchers a specific and sensitive tool for investigating the functions of KLF11 and exploring its implications in health and disease.
Product Name:
KLF11 Rabbit Polyclonal Antibody
SKU:
CAB18659
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 13-107 of human KLF11 (NP_003588.1).
The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8462
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using KLF11 antibody (CAB18659) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
