The KLF10 Polyclonal Antibody (CAB13180) is a valuable tool for researchers studying KLF10, a transcription factor involved in various cellular processes, including cell proliferation, differentiation, and apoptosis. This antibody, produced in rabbits, is highly specific to human samples and is suitable for Western blot applications.KLF10, also known as TGF-β-inducible early gene 1, plays a crucial role in mediating the effects of transforming growth factor beta (TGF-β) signaling, impacting gene expression and cellular responses to growth factors and cytokines. Dysregulation of KLF10 has been implicated in diseases such as cancer, fibrosis, and cardiovascular disorders, making it an important target for research.
The KLF10 Polyclonal Antibody binds specifically to the KLF10 protein, allowing for its detection and analysis in various cell types and tissues. This antibody is a valuable tool for investigating the role of KLF10 in disease development and progression, as well as for exploring its potential as a therapeutic target. Researchers in the fields of molecular biology, cell biology, and disease pathology will benefit from using the KLF10 Polyclonal Antibody in their studies.
Product Name:
KLF10 Rabbit Polyclonal Antibody
SKU:
CAB13180
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 161-365 of human KLF10 (NP_001027453.1).
This gene encodes a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
7071
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KLF10 Rabbit pAb (CAB13180) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
