The KLC2 Polyclonal Antibody (CAB17757) is a valuable tool for researchers studying KLC2, a kinesin light chain protein involved in intracellular transport processes. This antibody is raised in rabbits and has high reactivity with human samples, making it suitable for use in Western blot applications. By binding specifically to the KLC2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in cell biology and molecular biology.
KLC2 plays a crucial role in the transport of various cellular cargo, including organelles and proteins, along microtubules. Dysregulation of KLC2 has been implicated in various diseases, making it a target of interest for research in neurology, oncology, and more. Understanding the function and regulation of KLC2 can provide valuable insights into cellular transport mechanisms and potential therapeutic targets for related disorders.
Product Name:
KLC2 Rabbit Polyclonal Antibody
SKU:
CAB17757
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human KLC2 (NP_073733.1).
Sequence:
MAMM VFPR EEKL SQDE IVLG TKAV IQGL ETLR GEHR ALLA PLVA PEAG EAEP GSQE RCIL LRRS LEAI ELGL GEAQ VILA LSSH LGAV ES
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:2000
Synonyms:
KLC2; SPOAN
Positive Sample:
Raji,Mouse brain,Rat lung,Rat testis
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm, cytoskeleton.
Calculated MW:
69kDa
Observed MW:
69kDa
The protein encoded by this gene is a light chain of kinesin, a molecular motor responsible for moving vesicles and organelles along microtubules. Defects in this gene are a cause of spastic paraplegia, optic atrophy, and neuropathy (SPOAN) syndrome.
Purification Method:
Affinity purification
Gene ID:
64837
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KLC2 Rabbit pAb (CAB17757) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
