KIRREL2 Rabbit Polyclonal Antibody (CAB13130)
- SKU:
- CAB13130
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | KIRREL2 Rabbit Polyclonal Antibody |
SKU: | CAB13130 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-220 of human KIRREL2 (NP_954649.3). |
Sequence: | GPSP HFLQ QPED LVVL LGEE ARLP CALG AYWG LVQW TKSG LALG GQRD LPGW SRYW ISGN AANG QHDL HIRP VELE DEAS YECQ ATQA GLRS RPAQ LHVL VPPE APQV LGGP SVSL VAGV PANL TCRS RGDA RPTP ELLW FRDG VLLD GATF HQTL LKEG TPGS VEST LTLT PFSH DDGA TFVC RARS QALP TGRD TAIT |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 |
Synonyms: | NLG1; NEPH3; FILTRIN; KIRREL2 |
Positive Sample: | Mouse kidney,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass type I membrane protein. |
Calculated MW: | 75kDa |
Observed MW: | 95kDa |
This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter.
Purification Method: | Affinity purification |
Gene ID: | 84063 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |