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KIR2DL5A Monoclonal Antibody [PAT11C11AT] (CPAB0699)

SKU:
CPAB0699
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT11C11AT
Applications:
WB
ELISA
€149

Description

system_update_alt Datasheet

KIR2DL5A Monoclonal Antibody [PAT11C11AT] (CPAB0699)

The KIR2DL5A Antibody (CPAB0699) is a polyclonal antibody specifically designed for research involving the KIR2DL5A protein, a member of the killer cell immunoglobulin-like receptor (KIR) family. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blotting.KIR2DL5A is a cell surface receptor that plays a role in regulating immune responses, particularly in the context of natural killer (NK) cells. By binding to the KIR2DL5A protein, this antibody allows for the detection and analysis of KIR2DL5A expression in different cell types, making it a valuable tool for studies in immunology and cancer research.

The significance of KIR2DL5A in immune regulation and its potential implications in diseases like cancer and autoimmune disorders make it a promising target for further research. Understanding the function of KIR2DL5A is essential for developing new therapies that modulate immune responses and potentially treat various immune-related conditions.

Product Name:KIR2DL5A Antibody
Product Sku:CPAB0699
Size:5μg
Host Species:Mouse
Immunogen:Anti-human KIR2DL5A mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human KIR2DL5A amino acids 22-238 purified from Ecoli.
Clone:PAT11C11AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:KIR2DL5A antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:Killer cell immunoglobulin-like receptor 2DL5A or KIR2DL5A is part of the killer cell Ig-like receptor (KIR) family. KIR2DL5A is atype I transmembrane glycoprotein. The protein is detected on the cell membrane as a monomer who, once tyrosine is phosphorylated, recruits the Src homology region 2-includes protein tyrosine phosphatase-2. Hence, KIR2DL5A is an inhibitory receptor gathering a combination of genetic, structural, and functional features unique among KIR, suggesting that KIR2DL5A plays a crucial role in innate immunity.
Synonyms:Killer Cell Immunoglobulin Like Receptor, Two Ig Domains And Long Cytoplasmic Tail 5A, Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail 5A, KIR2DL5, CD158F, Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5, Killer Cell Immunoglobulin-Like Receptor KIR2DL5A, Killer Cell Immunoglobulin-Like Receptor 2DL5A, CD158f1 Antigen, KIR2DL5.1, KIR2DL5.3, CD158F1, KIR2DL5A.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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