The KIN Polyclonal Antibody (CAB17646) is a valuable tool for research involving the KIN protein, a key player in various cellular processes, including cell signaling and regulation. This antibody, derived from rabbits, exhibits high reactivity with human samples and is specifically validated for use in Western blot applications. By binding to the KIN protein, this antibody allows for detection and analysis in different cell types, making it an ideal choice for studies in cell biology and signaling pathways.
KIN, also known as Kin of IRRE like, is involved in crucial cellular functions such as cell growth, proliferation, and differentiation. Its role in signaling pathways makes it a promising target for research in areas like cancer biology, developmental biology, and neurobiology. Understanding the function of KIN is essential for unraveling its contribution to normal physiology and disease states, paving the way for potential therapeutic interventions targeting this protein.
Product Name:
KIN Rabbit Polyclonal Antibody
SKU:
CAB17646
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 180-270 of human KIN (NP_036443.1).
The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog. Alternative splicing of this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
22944
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KIN Rabbit pAb (CAB17646) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
