KIF7 Rabbit Polyclonal Antibody (CAB15581)
- SKU:
- CAB15581
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | KIF7 Rabbit Polyclonal Antibody |
SKU: | CAB15581 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1044-1343 of human KIF7 (NP_940927.2). |
Sequence: | QLDE AIEA LDAA IEYK NEAI TCRQ RVLR ASAS LLSQ CEMN LMAK LSYL SSSE TRAL LCKY FDKV VTLR EEQH QQQI AFSE LEMQ LEEQ QRLV YWLE VALE RQRL EMDR QLTL QQKE HEQN MQLL LQQS RDHL GEGL ADSR RQYE ARIQ ALEK ELGR YMWI NQEL KQKL GGVN AVGH SRGG EKRS LCSE GRQA PGNE DELH LAPE LLWL SPLT EGAP RTRE ETRD LVHA PLPL TWKR SSLC GEEQ GSPE ELRQ REAA EPLV GRVL PVGE AGLP WNFG PLSK PRRE LRRA SPGM IDVR KNPL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | ACLS; AGBK; HLS2; MMEDF; JBTS12; UNQ340; KIF7 |
Positive Sample: | Jurkat,LO2,A-549 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, cilium. |
Calculated MW: | 151kDa |
Observed MW: | 150kDa |
This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.
Purification Method: | Affinity purification |
Gene ID: | 374654 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |