The KIF6 Polyclonal Antibody (CAB7614) is a valuable tool for researchers studying the KIF6 protein, a member of the kinesin family of motor proteins. This antibody, raised in rabbits, has high reactivity with human samples and has been validated for use in various applications, including Western blotting.KIF6 is involved in intracellular transport and plays a crucial role in the movement of organelles and vesicles within cells. It is also implicated in processes such as cell division and cell migration. By using the KIF6 Polyclonal Antibody, researchers can detect and analyze the expression of KIF6 in different cell types, providing valuable insights into its function and potential implications in various biological processes.
Furthermore, studying KIF6 is particularly relevant in the context of cancer research, as aberrant expression or activity of kinesin proteins like KIF6 have been associated with tumorigenesis and cancer progression. Understanding the role of KIF6 could lead to the development of novel therapeutic strategies targeting this protein in cancer treatment. Researchers interested in investigating the molecular mechanisms involving KIF6 will find the KIF6 Polyclonal Antibody to be an essential tool in their studies.
Product Name:
KIF6 Rabbit Polyclonal Antibody
SKU:
CAB7614
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 565-814 of human KIF6 (NP_659464.3).
This gene encodes a member of a family of molecular motors which are involved in intracellular transport of protein complexes, membrane organelles, and messenger ribonucleic acid along microtubules. Kinesins function as homodimeric molecules with two N-terminal head domains that move along microtubules and two C-terminal tail domains that interact with the transported cargo, either directly or indirectly, through adapter molecules. This gene is ubiquitously expressed in coronary arteries and other vascular tissue. A naturally occurring mutation in this gene is associated with coronary heart disease.
Purification Method:
Affinity purification
Gene ID:
221458
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse testis, using KIF6 antibody (CAB7614) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
