The KIF5A Polyclonal Antibody (CAB3303) is a crucial tool for researchers studying KIF5A, a kinesin motor protein involved in intracellular transport and vesicle trafficking. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been rigorously validated for Western blotting applications. By specifically binding to the KIF5A protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in cell biology and neuroscience.
KIF5A plays a vital role in cellular processes such as organelle transport, nerve cell development, and synaptic transmission. Dysregulation of KIF5A has been associated with neurological disorders like Hereditary Spastic Paraplegia and Amyotrophic Lateral Sclerosis, highlighting the importance of understanding its function. The KIF5A Polyclonal Antibody provides researchers with a valuable tool for investigating the mechanisms underlying these diseases and developing potential therapeutic interventions.
Product Name:
KIF5A Rabbit Polyclonal Antibody
SKU:
CAB3303
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 933-1032 of human KIF5A (NP_004975.2).
This gene encodes a member of the kinesin family of proteins. Members of this family are part of a multisubunit complex that functions as a microtubule motor in intracellular organelle transport. Mutations in this gene cause autosomal dominant spastic paraplegia 10.
Purification Method:
Affinity purification
Gene ID:
3798
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KIF5A Rabbit pAb (CAB3303) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
