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KIF3C Antibody (PACO59764)

SKU:
PACO59764
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
IF
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
  • KIF3C Antibody PACO59764
  • KIF3C Antibody PACO59764
  • KIF3C Antibody PACO59764
$407

Description

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KIF3C Antibody (PACO59764)

The KIF3C Polyclonal Antibody (PACO59764) is a valuable tool for researchers studying KIF3C, a kinesin motor protein involved in intracellular transport and cell division. This antibody, produced in rabbits, exhibits high specificity and reactivity with human samples, making it an ideal choice for Western blot applications. By targeting the KIF3C protein, this antibody enables precise detection and analysis in a variety of cell types, supporting investigations in cell biology, molecular biology, and cancer research.

KIF3C is a key player in cellular processes such as organelle transport, ciliary assembly, and cell division, making it essential for maintaining proper cell function and structure. Dysregulation of KIF3C has been linked to various diseases, including cancer and neurodegenerative disorders, highlighting its potential as a therapeutic target. By studying the role of KIF3C in health and disease, researchers can uncover novel insights into cellular dynamics and develop targeted therapies for a range of conditions.

Antibody Name:KIF3C Antibody (PACO59764)
Antibody SKU:PACO59764
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC, IF
Recommended Dilutions:ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:200-1:500
Species Reactivity:Human
Immunogen:Recombinant Human Kinesin-like protein KIF3C protein (158-267AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageWestern Blot. Positive WB detected in: Hela whole cell lysate, K562 whole cell lysate. All lanes: KIF3C antibody at 4.2µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 90 kDa. Observed band size: 90 kDa.
Product ImageImmunofluorescence staining of A549 cells with PACO59764 at 1:200, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Product ImageIHC image of PACO59764 diluted at 1:600 and staining in paraffin-embedded human glioma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:Microtubule-based anterograde translocator for membranous organelles.
Synonyms:Kinesin-like protein KIF3C, KIF3C
UniProt Protein Function:KIF3C: Microtubule-based anterograde translocator for membranous organelles. Belongs to the kinesin-like protein family. Kinesin II subfamily.Protein type: Microtubule-binding; MotorChromosomal Location of Human Ortholog: 2p23Cellular Component: cytosol; kinesin complexMolecular Function: ATPase activity; microtubule motor activity; motor activityBiological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; microtubule-based movement; retrograde vesicle-mediated transport, Golgi to ER
UniProt Protein Details:
NCBI Summary:
UniProt Code:O14782
NCBI GenInfo Identifier:308153589
NCBI Gene ID:3797
NCBI Accession:O14782.3
UniProt Secondary Accession:O14782,O43544, Q4ZG18, Q53SX5, Q562F7
UniProt Related Accession:O14782
Molecular Weight:89,426 Da
NCBI Full Name:Kinesin-like protein KIF3C
NCBI Synonym Full Names:kinesin family member 3C
NCBI Official Symbol:KIF3C  
NCBI Official Synonym Symbols:
NCBI Protein Information:kinesin-like protein KIF3C
UniProt Protein Name:Kinesin-like protein KIF3C
UniProt Synonym Protein Names:
Protein Family:Kinesin-like protein
UniProt Gene Name:KIF3C  
UniProt Entry Name:KIF3C_HUMAN
Antibodies
KIF3C Antibody (PACO10104)
Secondary Antibody
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)
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Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011)
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