The KIF3A Polyclonal Antibody (CAB6639) is a valuable tool for researchers studying KIF3A, a member of the kinesin superfamily of proteins that plays a crucial role in intracellular transport and cell division. This antibody, generated in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By binding to the KIF3A protein, researchers can effectively study its function and localization in various cell types.KIF3A is known to be involved in diverse cellular processes, including vesicle and organelle transport, ciliary assembly, and mitotic spindle formation.
Dysregulation of KIF3A has been linked to diseases such as ciliopathies, cancer, and neurodegenerative disorders, highlighting its importance in cellular homeostasis and disease pathology. The KIF3A Polyclonal Antibody enables researchers to investigate the role of KIF3A in these physiological and pathological processes, paving the way for potential therapeutic interventions targeting KIF3A-related pathways.
Product Name:
KIF3A Rabbit Polyclonal Antibody
SKU:
CAB6639
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 430-699 of human KIF3A (NP_008985.3).
Enables protein phosphatase binding activity; small GTPase binding activity; and spectrin binding activity. Involved in protein localization to cell junction and protein transport. Located in centriole and centrosome. Part of kinesin II complex. Colocalizes with spindle microtubule.
Purification Method:
Affinity purification
Gene ID:
11127
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using KIF3A Rabbit pAb (CAB6639) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
