The KIF2C Polyclonal Antibody (CAB5449) is a powerful tool for researchers studying KIF2C, a kinesin protein essential for microtubule dynamics and cell division. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for Western blotting applications.KIF2C, also known as kinesin family member 2C, is involved in chromosome segregation during mitosis and is crucial for proper cell division. Dysregulation of KIF2C has been linked to various types of cancer, highlighting its potential as a therapeutic target for cancer treatment.
By targeting KIF2C with this antibody, researchers can further explore its role in cancer progression and potentially develop novel treatment strategies.Overall, the KIF2C Polyclonal Antibody (CAB5449) is a valuable tool for investigating the functions and mechanisms of KIF2C in cellular processes, particularly in the context of cancer research. Its high reactivity and specificity make it a reliable choice for studying KIF2C expression and function in various experimental settings.
Product Name:
KIF2C/MCAK Rabbit Polyclonal Antibody
SKU:
CAB5449
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human KIF2C/MCAK (NP_006836.2).
This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromosome segregation. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
11004
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using KIF2C/MCAK Rabbit pAb (CAB5449) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.