The KIF22 Polyclonal Antibody (CAB15285) is a valuable tool for researchers studying KIF22, a kinesin-like protein involved in cell division and intracellular transport processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the KIF22 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for investigations in cell biology and cancer research.KIF22 plays a crucial role in regulating mitotic spindle dynamics and chromosome segregation during cell division, making it an important target for studies on cell proliferation and tumor formation.
Understanding KIF22's function is essential for unraveling its potential implications in cancer development and identifying novel therapeutic strategies. The use of the KIF22 Polyclonal Antibody provides researchers with a reliable tool for investigating the intricate mechanisms underlying cell division and its relevance to disease processes.
Product Name:
KIF22 Rabbit Polyclonal Antibody
SKU:
CAB15285
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 456-665 of human KIF22 (NP_015556.1).
The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3835
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KIF22 Rabbit pAb (CAB15285) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
