The KIF21A Polyclonal Antibody (CAB16548) is a valuable tool for researchers studying KIF21A, a kinesin-like protein that plays a crucial role in cellular transport and organelle positioning. This antibody, produced in rabbits, is highly specific to human samples, making it an ideal choice for Western blot applications.KIF21A is essential for various cellular processes, including intracellular transport and neuronal development. Dysregulation of KIF21A has been linked to neurological disorders such as hereditary spastic paraplegia and intellectual disabilities.
By targeting the KIF21A protein, researchers can gain insights into its functions and potential implications in disease pathology.This polyclonal antibody enables the detection and analysis of KIF21A in different cell types, making it a versatile tool for studies in neuroscience, cell biology, and developmental biology. Its high reactivity and specificity make it a reliable choice for researchers looking to unravel the complexities of KIF21A function and its role in health and disease.
Product Name:
KIF21A Rabbit Polyclonal Antibody
SKU:
CAB16548
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1070-1270 of human KIF21A (NP_001166935.1).
This gene encodes a member of the KIF4 subfamily of kinesin-like motor proteins. The encoded protein is characterized by an N-terminal motor domain a coiled-coil stalk domain and a C-terminal WD-40 repeat domain. This protein may be involved in microtubule dependent transport. Mutations in this gene are the cause of congenital fibrosis of extraocular muscles-1. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
55605
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KIF21A Rabbit pAb (CAB16548) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
