The KIF20B Polyclonal Antibody (CAB15360) is a versatile tool for researchers studying KIF20B, a kinesin motor protein involved in cell division and cytokinesis. This antibody is produced in rabbits and is highly specific for human samples, making it ideal for a variety of applications including Western blot and immunofluorescence.KIF20B is essential for the proper segregation of chromosomes during cell division, making it a key player in maintaining genomic stability.
Dysregulation of KIF20B has been implicated in various diseases, including cancer, where aberrant cell division can lead to tumor formation.By utilizing the KIF20B Polyclonal Antibody, researchers can explore the function and localization of KIF20B in different cell types, providing valuable insights into its role in cellular processes. This antibody is a valuable tool for those studying cell biology, cancer biology, and mechanisms of cell division.
Product Name:
KIF20B Rabbit Polyclonal Antibody
SKU:
CAB15360
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1200-1500 of human KIF20B (NP_057279.2).
Cell projection, Cytoplasm, Midbody, Nucleus, axon, centrosome, cytoskeleton, growth cone, microtubule organizing center, nucleolus, nucleoplasm, spindle, spindle pole.
Calculated MW:
211kDa
Observed MW:
210kDa
Enables several functions, including WW domain binding activity; plus-end-directed microtubule motor activity; and protein homodimerization activity. Involved in positive regulation of cell population proliferation and positive regulation of cytokinesis. Located in several cellular components, including microtubule cytoskeleton; midbody; and nuclear lumen.
Purification Method:
Affinity purification
Gene ID:
9585
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KIF20B Rabbit pAb (CAB15360) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.