The KIF20A Polyclonal Antibody (CAB15377) is a vital tool for researchers studying KIF20A, a kinesin motor protein that plays a crucial role in cell division and cytokinesis. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blotting applications. By binding specifically to the KIF20A protein, this antibody allows for the detection and analysis of KIF20A in various cell types, making it ideal for studies in cell biology and cancer research.KIF20A, also known as MKLP2, is essential for the proper completion of cell division as it regulates the formation and stability of the mitotic spindle during cytokinesis.
Dysregulation of KIF20A has been linked to abnormal cell division and cancer progression, making it a promising target for therapeutic interventions. By understanding the functions and mechanisms of KIF20A, researchers can gain valuable insights into the development of novel treatments for cancer and other diseases characterized by aberrant cell division.
Product Name:
KIF20A Rabbit Polyclonal Antibody
SKU:
CAB15377
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 591-890 of human KIF20A (NP_005724.1).
Enables protein kinase binding activity. Involved in microtubule bundle formation; midbody abscission; and regulation of cytokinesis. Located in several cellular components, including cleavage furrow; intercellular bridge; and midbody. Implicated in restrictive cardiomyopathy.
Purification Method:
Affinity purification
Gene ID:
10112
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KIF20A Rabbit pAb (CAB15377) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
