The KIF17 Polyclonal Antibody (CAB16562) is a valuable tool for researchers studying KIF17, a kinesin motor protein involved in intracellular transport processes. Raised in rabbits, this antibody is highly specific for human samples and has been validated for use in Western blot applications. By targeting the KIF17 protein, this antibody allows for the detection and analysis of KIF17 expression in various cell types, making it ideal for investigations in cellular biology and neurology research.
KIF17 is known to be crucial for the transport of organelles and proteins along microtubules within cells, playing a significant role in neuronal development and function. Dysregulation of KIF17 has been linked to neurodegenerative diseases and cognitive disorders, making it a promising target for therapeutic interventions. Understanding the mechanisms and functions of KIF17 is essential for advancing knowledge in these areas and potentially developing targeted treatments in the future.
Product Name:
KIF17 Rabbit Polyclonal Antibody
SKU:
CAB16562
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 360-660 of human KIF17 (NP_001116291).
Predicted to enable microtubule binding activity and plus-end-directed microtubule motor activity. Predicted to be involved in anterograde dendritic transport of neurotransmitter receptor complex and cell projection organization. Predicted to act upstream of or within microtubule-based process; protein-containing complex localization; and vesicle-mediated transport. Predicted to be located in microtubule cytoskeleton. Predicted to be part of intraciliary transport particle B and kinesin complex. Predicted to be active in cilium; microtubule cytoskeleton; and neuron projection.
Purification Method:
Affinity purification
Gene ID:
57576
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KIF17 Rabbit pAb (CAB16562) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
