The KIF13A Polyclonal Antibody (CAB15880) is specifically designed for research involving the KIF13A protein, a kinesin motor protein known for its role in intracellular transport and cell division. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By targeting the KIF13A protein, this antibody allows for the detection and analysis of KIF13A in various cell types, making it an ideal tool for studies in cell biology and cancer research.
KIF13A is a crucial player in the intracellular transport of vesicles and organelles within cells, as well as in the regulation of cell division processes. Its importance in these cellular functions makes it a valuable target for research aimed at understanding diseases such as cancer, neurodegenerative disorders, and developmental abnormalities. Investigating the function of KIF13A is vital for uncovering new insights into cellular processes and potential therapeutic targets for various diseases.
Product Name:
KIF13A Rabbit Polyclonal Antibody
SKU:
CAB15880
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1300-1600 of human KIF13A (NP_001099036.1).
This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
63971
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from LO2 cells, using KIF13A Rabbit pAb (CAB15880) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
