The EG5 Rabbit Monoclonal Antibody (CAB4659) is a cutting-edge research tool designed for studies involving EG5, a motor protein essential for cell division. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards EG5 in human samples, making it a reliable tool for Western blot analysis. By targeting the EG5 protein, researchers can investigate various cellular processes related to cell division and explore its potential role in cancer development.EG5, also known as kinesin spindle protein, plays a crucial role in the formation and function of the mitotic spindle during cell division.
Dysregulation of EG5 has been linked to abnormal cell division and tumor growth, making it a promising therapeutic target in cancer research. By studying the function and regulation of EG5, researchers can gain insights into the mechanisms of cell division and potentially develop novel treatments for cancer and other proliferative disorders.Overall, the EG5 Rabbit Monoclonal Antibody (CAB4659) offers a valuable tool for investigating the role of EG5 in cellular processes and disease development, providing a foundation for advanced research in cell biology and oncology.
Product Name:
EG5/KIF11 Rabbit Monoclonal Antibody
SKU:
CAB4659
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 900-1056 of human EG5/KIF11 (P52732).
This gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis.
Purification Method:
Affinity purification
Gene ID:
3832
Clone Number:
ARC1080
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using EG5/KIF11 Rabbit mAb (CAB4659) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
