The KIAA0319 Polyclonal Antibody (CAB15369) is a valuable tool for researchers investigating the function of the KIAA0319 protein, a molecule associated with dyslexia and neuronal migration. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the KIAA0319 protein, researchers can effectively detect and analyze its expression in various cells and tissues.KIAA0319 is known for its role in regulating neuronal migration during brain development, making it a key target for studies in neurobiology and neurodevelopmental disorders such as dyslexia.
Understanding the function of KIAA0319 can provide valuable insights into the mechanisms underlying these conditions and potentially lead to the development of targeted therapies.Overall, the KIAA0319 Polyclonal Antibody (CAB15369) offers researchers a reliable tool for investigating the function of the KIAA0319 protein in both normal and pathological conditions, furthering our understanding of neurodevelopment and associated disorders.
Product Name:
KIAA0319 Rabbit Polyclonal Antibody
SKU:
CAB15369
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-300 of human KIAA0319 (NP_055624.2).
Cell membrane, Early endosome membrane, Single-pass type I membrane protein.
Calculated MW:
118kDa
Observed MW:
118kDa
This gene encodes a transmembrane protein that contains a large extracellular domain with multiple polycystic kidney disease (PKD) domains. The encoded protein may play a role in the development of the cerebral cortex by regulating neuronal migration and cell adhesion. Single nucleotide polymorphisms in this gene are associated with dyslexia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
9856
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KIAA0319 Rabbit pAb (CAB15369) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 5s.
