The KHDRBS3 Polyclonal Antibody (CAB6637) is a key tool for researchers studying KHDRBS3, a RNA-binding protein involved in RNA metabolism and splicing regulation. This antibody, developed in rabbits, exhibits high reactivity towards human samples and is validated for use in Western blot applications. By binding specifically to the KHDRBS3 protein, this antibody enables precise detection and analysis in various cell types, making it ideal for studies in molecular biology and gene expression research.
KHDRBS3, also known as Sam68, plays a crucial role in post-transcriptional regulation of gene expression, influencing processes such as RNA splicing, stability, and translation. Its involvement in RNA metabolism makes it a promising target for understanding diseases like cancer, neurological disorders, and viral infections. Investigating the function of KHDRBS3 is essential for uncovering potential therapeutic strategies that target RNA processing pathways in these pathological conditions.
Product Name:
KHDRBS3 Rabbit Polyclonal Antibody
SKU:
CAB6637
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 177-346 of human KHDRBS3 (NP_006549.1).
Enables RNA binding activity; identical protein binding activity; and protein domain specific binding activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome and spermatogenesis. Located in nucleoplasm. Part of protein-containing complex.
Purification Method:
Affinity purification
Gene ID:
10656
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using KHDRBS3 antibody (CAB6637) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.