The KHDBRS1 Polyclonal Antibody (CAB6101) is a valuable tool for research involving the KHDBRS1 protein, a key regulator of RNA metabolism and processing. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in a variety of applications, with a particular emphasis on immunohistochemistry and western blotting.KHDBRS1, also known as Sam68, is a multifunctional RNA-binding protein that plays a critical role in alternative splicing and gene expression. Its dysregulation has been implicated in various diseases, including cancer and neurological disorders.
By using the KHDBRS1 Polyclonal Antibody, researchers can analyze the expression and localization of KHDBRS1 in different cell types and tissues, providing valuable insights into its function and potential therapeutic implications.Overall, the KHDBRS1 Polyclonal Antibody is a versatile tool for studying RNA processing mechanisms and identifying potential therapeutic targets in diseases associated with dysregulated gene expression. Its high specificity and reliable performance make it a valuable asset for researchers in the fields of molecular biology, cancer biology, and neuroscience.
Product Name:
KHDRBS1/Sam68 Rabbit Polyclonal Antibody
SKU:
CAB6101
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 343-443 of human KHDRBS1/Sam68 (NP_006550.1).
This gene encodes a member of the K homology domain-containing, RNA-binding, signal transduction-associated protein family. The encoded protein appears to have many functions and may be involved in a variety of cellular processes, including alternative splicing, cell cycle regulation, RNA 3'-end formation, tumorigenesis, and regulation of human immunodeficiency virus gene expression. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10657
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using KHDRBS1/Sam68 Rabbit pAb (CAB6101) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.