KEAP1 Rabbit Polyclonal Antibody (CAB17062)
- SKU:
- CAB17062
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | KEAP1 Rabbit Polyclonal Antibody |
SKU: | CAB17062 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 301-400 of human KEAP1 (NP_036421.2). |
Sequence: | LVKI FEEL TLHK PTQV MPCR APKV GRLI YTAG GYFR QSLS YLEA YNPS DGTW LRLA DLQV PRSG LAGC VVGG LLYA VGGR NNSP DGNT DSSA LDCY NPMT |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | INrf2; KLHL19; KEAP1 |
Positive Sample: | Mouse brain,Rat brain |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 70kDa |
Observed MW: | 60-64kDa |
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 9817 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |