The KDM7A Polyclonal Antibody (CAB8266) is a valuable tool for researchers studying KDM7A, a histone demethylase involved in gene expression regulation and epigenetic modifications. This antibody, produced in rabbits, exhibits high specificity and sensitivity in detecting KDM7A in human samples, making it an essential component for Western blot experiments.KDM7A, also known as Lysine Demethylase 7A, plays a crucial role in the control of gene transcription by removing methyl groups from histone proteins. Dysregulation of KDM7A has been associated with various diseases, including cancer and developmental disorders.
Therefore, the precise detection and analysis of KDM7A expression levels are essential for understanding its biological functions and exploring its potential as a therapeutic target.With its reliable performance and broad applicability in different cell types, the KDM7A Polyclonal Antibody is an indispensable tool for investigating the role of KDM7A in epigenetic regulation and disease pathology. Whether studying cancer biology, developmental processes, or epigenetic mechanisms, this antibody provides researchers with a valuable resource for advancing their scientific inquiries.
Product Name:
KDM7A Rabbit Polyclonal Antibody
SKU:
CAB8266
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 21-120 of mouse KDM7A (NP_001028602.2).
Enables histone H3-methyl-lysine-9 demethylase activity and histone H3-tri/di-methyl-lysine-27 demethylase activity. Involved in histone H3-K27 demethylation; histone H3-K9 demethylation; and positive regulation of transcription, DNA-templated. Predicted to be located in nucleolus and nucleoplasm. Human ortholog(s) of this gene implicated in melanoma. Orthologous to human KDM7A (lysine demethylase 7A).
Purification Method:
Affinity purification
Gene ID:
338523
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using KDM7A Rabbit pAb (CAB8266) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
