The KDM7A Polyclonal Antibody (CAB14692) is a valuable tool for research involving KDM7A, a histone demethylase enzyme with critical roles in epigenetic regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot and immunohistochemistry applications.KDM7A is known to play a key role in gene expression regulation through histone modification processes, making it a key player in cellular processes such as differentiation, development, and DNA damage response. The KDM7A Polyclonal Antibody binds specifically to the KDM7A protein, enabling precise detection and analysis in various cell types.
Given the importance of KDM7A in epigenetic regulation and its potential implications in various diseases, this antibody is an essential tool for researchers investigating the role of KDM7A in cancer, developmental disorders, and other conditions related to epigenetic dysregulation. By understanding the function of KDM7A, researchers can uncover new insights into disease mechanisms and potentially develop targeted therapies to address these conditions.
Product Name:
KDM7A Rabbit Polyclonal Antibody
SKU:
CAB14692
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 100-200 of mouse KDM7A (NP_001028602.2).
Enables histone H3-methyl-lysine-9 demethylase activity and histone H3-tri/di-methyl-lysine-27 demethylase activity. Involved in histone H3-K27 demethylation; histone H3-K9 demethylation; and positive regulation of transcription, DNA-templated. Predicted to be located in nucleolus and nucleoplasm. Human ortholog(s) of this gene implicated in melanoma. Orthologous to human KDM7A (lysine demethylase 7A).
Purification Method:
Affinity purification
Gene ID:
338523
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of T-47d, using KDM7A Rabbit pAb (CAB14692) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
