The KDM5C Polyclonal Antibody (CAB15740) is a valuable tool for researchers studying KDM5C, a key protein involved in epigenetic regulation. This antibody, produced in rabbits, exhibits strong reactivity with human samples and has been validated for use in various applications, including Western blotting. By specifically binding to the KDM5C protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential component for studies in epigenetics and gene regulation.
KDM5C, also known as lysine demethylase 5C, plays a crucial role in chromatin remodeling and gene expression regulation. Dysregulation of KDM5C has been linked to various diseases, including cancer and neurodevelopmental disorders, making it a promising target for therapeutic interventions. Investigating the function of KDM5C is essential for gaining insights into its role in disease development and progression, ultimately leading to the development of novel treatment strategies.
Product Name:
KDM5C Rabbit Polyclonal Antibody
SKU:
CAB15740
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1400 to the C-terminus of human KDM5C (XP_011529128.1).
This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked cognitive disability. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
8242
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using KDM5C antibody (CAB15740) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
