[KO Validated] KDM5B Rabbit Polyclonal Antibody (CAB7772)
- SKU:
- CAB7772
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] KDM5B Rabbit Polyclonal Antibody |
SKU: | CAB7772 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 784-883 of human KDM5B (NP_006609.3). |
Sequence: | EESE MKKF PDND LLRH LRLV TQDA EKCA SVAQ QLLN GKRQ TRYR SGGG KSQN QLTV NELR QFVT QLYA LPCV LSQT PLLK DLLN RVED FQQH SQKL LSEE |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | CT31; PLU1; PUT1; MRT65; PLU-1; JARID1B; PPP1R98; RBP2-H1; RBBP2H1A; 5B |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 176kDa |
Observed MW: | 176kDa |
This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 10765 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |