KDM4B/JMJD2B Rabbit Polyclonal Antibody (CAB5824)
- SKU:
- CAB5824
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | KDM4B/JMJD2B Rabbit Polyclonal Antibody |
SKU: | CAB5824 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-365 of human KDM4B/JMJD2B (NP_055830.1). |
Sequence: | MGSE DHGA QNPS CKIM TFRP TMEE FKDF NKYV AYIE SQGA HRAG LAKI IPPK EWKP RQTY DDID DVVI PAPI QQVV TGQS GLFT QYNI QKKA MTVG EYRR LANS EKYC TPRH QDFD DLER KYWK NLTF VSPI YGAD ISGS LYDD DVAQ WNIG SLRT ILDM VERE CGTI IEGV NTPY LYFG MWKT TFAW HTED MDLY SINY LHFG EPKS WYAI PPEH GKRL ERLA IGFF PGSS QGCD AFLR HKMT LISP IILK KYGI PFSR ITQE AGEF MITF PYGY HAGF NHGF NCAE STNF ATLR WIDY GKVA TQCT CRKD MVKI SMDV FVRI LQPE RYEL WKQG KDLT VLDH TRPT ALTS PELS SWSA SRAS L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | MRD65; JMJD2B; TDRD14B; KDM4B/JMJD2B |
Positive Sample: | Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 122kDa |
Observed MW: | 150kDa |
Enables histone H3-methyl-lysine-36 demethylase activity and histone H3-methyl-lysine-9 demethylase activity. Involved in histone H3-K36 demethylation and histone H3-K9 demethylation. Located in cytosol and nucleoplasm. Implicated in autosomal dominant non-syndromic intellectual disability; breast cancer; colorectal cancer; malignant peripheral nerve sheath tumor; and stomach cancer. Biomarker of several diseases, including alopecia areata; lung cancer; medulloblastoma; prostate cancer; and stomach cancer.
Purification Method: | Affinity purification |
Gene ID: | 23030 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |