KDM4B/JMJD2B Rabbit Monoclonal Antibody (CAB6670)
- SKU:
- CAB6670
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | KDM4B/JMJD2B Rabbit Monoclonal Antibody |
SKU: | CAB6670 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human KDM4B/JMJD2B (O94953). |
Sequence: | PPKE WKPR QTYD DIDD VVIP APIQ QVVT GQSG LFTQ YNIQ KKAM TVGE YRRL ANSE KYCT PRHQ DFDD LERK YWKN LTFV SPIY GADI SGSL YDDD VAQW N |
Tested Applications: | WB IF/ICC IP ChIP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cellsChIP,5μg antibody for 10μg-15μg of Chromatin |
Synonyms: | MRD65; JMJD2B; TDRD14B; KDM4B/JMJD2B |
Positive Sample: | HCT 116,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 122kDa |
Observed MW: | 150kDa |
Enables histone H3-methyl-lysine-36 demethylase activity and histone H3-methyl-lysine-9 demethylase activity. Involved in histone H3-K36 demethylation and histone H3-K9 demethylation. Located in cytosol and nucleoplasm. Implicated in autosomal dominant non-syndromic intellectual disability; breast cancer; colorectal cancer; malignant peripheral nerve sheath tumor; and stomach cancer. Biomarker of several diseases, including alopecia areata; lung cancer; medulloblastoma; prostate cancer; and stomach cancer.
Purification Method: | Affinity purification |
Gene ID: | 23030 |
Clone Number: | ARC1416 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |