The KDM3A Polyclonal Antibody (CAB11960) is a powerful tool for researchers studying KDM3A, a key player in epigenetic regulation. This antibody, produced in rabbits, exhibits high specificity for human samples and has been verified for use in Western blot experiments. By binding to the KDM3A protein, this antibody enables precise detection and analysis in various cell types, making it an essential resource for studies in genetics, cancer research, and developmental biology.KDM3A, also known as lysine-specific demethylase 3A, is a histone-modifying enzyme that plays a crucial role in gene expression regulation. Its involvement in chromatin remodeling and transcriptional activation makes it a target of interest in understanding cellular differentiation, proliferation, and disease progression.
Research on KDM3A has implications for uncovering new therapeutic targets in cancer, metabolic disorders, and other diseases related to epigenetic dysregulation.By using the KDM3A Polyclonal Antibody (CAB11960), scientists can delve deeper into the molecular mechanisms governed by KDM3A and uncover its impact on various biological processes. This antibody is a valuable asset for investigations aiming to elucidate the complex interplay between epigenetic modifications and cellular functions, paving the way for innovative therapeutic strategies and personalized medicine approaches.
Product Name:
KDM3A Rabbit Polyclonal Antibody
SKU:
CAB11960
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 975-1283 of human KDM3A (NP_060903.2).
Enables androgen receptor binding activity; histone H3-methyl-lysine-9 demethylase activity; and iron ion binding activity. Involved in several processes, including androgen receptor signaling pathway; formaldehyde biosynthetic process; and histone H3-K9 demethylation. Located in nucleoplasm. Implicated in cervical cancer and colon cancer. Biomarker of Ewing sarcoma; hepatocellular carcinoma; nasopharynx carcinoma; and prostate cancer.
Purification Method:
Affinity purification
Gene ID:
55818
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using KDM3A Rabbit pAb (CAB11960) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
