The Rhot1/Miro1 Polyclonal Antibody (CAB10008) is a valuable tool for researchers studying mitochondrial dynamics and function. Raised in rabbits, this antibody is highly specific for the Rhot1/Miro1 protein and has been validated for use in various applications, including Western blot and immunofluorescence.Rhot1/Miro1 is a key regulator of mitochondrial trafficking and distribution within cells, playing a crucial role in maintaining cellular homeostasis and energy production. Dysregulation of Rhot1/Miro1 has been linked to various diseases, including neurodegenerative disorders and cancer.
By targeting this protein, researchers can gain insights into mitochondrial function and its impact on cellular health.With its high specificity and sensitivity, the Rhot1/Miro1 Polyclonal Antibody is an essential tool for investigating the role of mitochondrial dynamics in health and disease. Whether studying mitochondrial transport in neuronal cells or examining mitochondrial morphology in cancer cells, this antibody enables precise detection and analysis of Rhot1/Miro1, advancing our understanding of cellular biology and disease pathways.
Product Name:
[KD Validated] RHOT1/MIRO1 Polyclonal Antibody
SKU:
CAB22551
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 310-590 of human RHOT1/MIRO1. (NP_060777.3).
Predicted to enable GTP binding activity and GTPase activity. Involved in cellular homeostasis; mitochondrial outer membrane permeabilization; and mitochondrion transport along microtubule. Is integral component of mitochondrial outer membrane.
Purification Method:
Affinity purification
Gene ID:
55288
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using [KD Validated] RHOT1/MIRO1 Rabbit pAb (CAB22551) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.