null

[KD Validated] NUR77 Monoclonal Antibody (CAB24016)

SKU:
CAB24016
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
$167 - $635
Frequently bought together:

Description

[KD Validated] NUR77 Monoclonal Antibody (CAB24016)

The KD Validated Nur77 Monoclonal Antibody is a specialized research tool designed for the study of Nur77, a nuclear receptor protein involved in various cellular processes, including apoptosis, inflammation, and metabolism. This antibody, developed through a rigorous validation process, specifically recognizes Nur77 in human samples and is suitable for use in Western blot applications.Nur77, also known as NR4A1, is a key regulator of gene expression and cell signaling pathways that play crucial roles in various physiological and pathological conditions. By targeting Nur77 with this monoclonal antibody, researchers can gain valuable insights into the function and regulation of this important protein, making it an essential tool for studies in cell biology, cancer research, and drug discovery.

With its high specificity and sensitivity, the KD Validated Nur77 Monoclonal Antibody offers researchers a reliable means of detecting and quantifying Nur77 protein levels in different cellular contexts, providing a deeper understanding of its role in health and disease. Whether investigating Nur77's impact on cell survival, inflammation, or metabolic pathways, this antibody is a valuable asset for advancing scientific knowledge and developing novel therapeutic strategies.

Product Name:[KD Validated] NUR77 Monoclonal Antibody
Product Code:CAB24016
Reactivity:Human, Mouse
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC58221
Reactivity:Human, Mouse
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:HeLa, PC-3
Cellular Location:Cytoplasm, Nucleus

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 250-350 of human NUR77 (NP_002126.2)
Sequence:PSLAQ SPLKL FPSQA THQLG EGESY SMPTA FPGLA PTSPH LEGSG ILDTP VTSTK ARSGA PGGSE GRCAV CGDNA SCQHY GVRTC EGCKG FFKRT VQKNA K
Synonyms:HMR, N10, TR3, NP10, GFRP1, NAK-1, NGFIB, NUR77
Calculated MW:64kDa
Observed MW:64kDa

Related Products